Post-doctoral fellow

We are seeking a motivated colleague to fill in the open position of a Post-doctoral fellow at the Laboratory of Biomolecular Interactions and Transport (www.labbit.eu) in SONATA BIS project funded by NCN. The position will be available as of October 1st, 2018. The successful candidate will study mechanisms governing the transport of multiple ligands via transport tunnels in enzymes, to disclose roles of direct interactions among ligands as well as allosteric effects on the tunnels mediated by protein-ligand interactions, and be involved in the development of novel methods. Such research will lead to the identification of structural features responsible for the cooperativity and interference among ligands. The acquired knowledge will be crucial for enabling discoveries of the molecular origins of transport-related pathologies, improvements of binding kinetics of inhibitors, and engineering of improved biocatalysts. The laboratory is located in Poznan, Poland, and is jointly affiliated to the International Institute of Molecular and Cell Biology in Warsaw and the Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University in Poznan – both rank among the top research institutes in Poland.

Requirements:
• Ph.D. in Biophysics, Bioinformatics, Computational Chemistry, Biochemistry, or related field awarded in 2011 and later (subject to extension in specific circumstances such as maternity/paternity leave/illness); candidates receiving their degrees by August 2018 might also be considered
• documented expertise in molecular dynamics simulations,
• good knowledge of Linux OS, experience with Markov state modeling would be considered important asset
• high motivation and enthusiasm, independence and reliability
• fluency in English, both spoken and written

Our offer:
• full-time employment contract, initially for 12 months with possible extension based on performance
• gross salary about 7,600 PLN/month (about €1,800); note that living costs in Poland are very favorable
• friendly, dynamic and supportive environment
• opportunity to develop leadership skills

How to apply:
Please send your applications or additional questions to Prof. Jan Brezovsky: Ten adres pocztowy jest chroniony przed spamowaniem. Aby go zobaczyć, konieczne jest włączenie w przeglądarce obsługi JavaScript. by April 30, 2018. The selected candidates will be invited for an interview taking place in May 2018. The application should be prepared as a single PDF file in English and contain:
• one-page cover letter describing your motivation
• Curriculum Vitae including a complete list of publications
• a list of three most significant scientific achievements, containing a brief explanation why you consider them so
• two letters of recommendation - at least one should be from your direct supervisor
• a scan of your university degree certificates/diplomas
• please include the following statement in your application: “I hereby give consent for my personal data included in my application to be processed for the purposes of the recruitment process under the Personal Data Protection Act as of 29 August 1997, consolidated text: Journal of Laws 2016, item 922 as amended.”

Selected publications:
• ACS Catalysis 6: 7597-7610, 2016
• Nucleic Acids Research 44: W479-487, 2016
• Nature Chemical Biology 10: 428-430, 2014
• Methods in Molecular Biology 1685: 25-42,2018
• Biotechnology Advances 31: 38-49, 2013
• Journal of Chemical Information and Modeling 55: 54-62, 2015