PhD student

Laboratory of Iron Homeostasis at the International Institute of Molecular and Cell Biology (IIMCB), Warsaw, headed by Katarzyna Mleczko-Sanecka, PhD is looking for a two PhD students. You will join the project entitled “Identifying unique adaptive responses of red pulp macrophages to iron deficiency” carried out as the SONATA grant (UMO-2020/38/E/NZ4/00511) of the National Science Centre, Poland.

The project aims to significantly advance our understanding of an organism’s adaptation to iron deficiency. Specifically, we identified that low body iron supplies trigger specific but still elusive mechanisms that alter functions of splenic red pulp macrophages, cells that phagocytose aged erythrocytes and thus are responsible for body iron recycling. Our further work aims now to better understand these adaptive responses and determine their physiological role for the whole organism.

One of PhD students will be responsible for comprehensively characterization of the functional adaptation of RPMs to iron deficiency and identification of its molecular triggers. He/she will also determine how this ‘rewiring’ affects RPMs’ inflammatory status. The second PhD student will explore how the abrogation of this ‘adaptation program’ affects the organism, including iron and blood homeostasis. To this end, he/she will employ new conditional knock-out mice characterized by specific suppression of the RPMs’ adaptation to low iron conditions.

The admissions process is conducted through the Doctoral School website system. The PhD student can apply to this specific project carried out as part of the Warsaw-4-PhD doctoral school via website (the application system will be activated from 24^th May, deadline for sending application is 6^th, June). For more information, please follow the link https://bit.ly/3g5tOtV

Candidates will be selected according to the procedure complying the rules for granting scholarships for young scientists in research projects funded by the National Science Centre (NCN Council Resolution No. 25/2019 dated March 14, 2019 r.), recruitment procedure for the Warsaw-4-PhD and the procedure complying with the rules of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers as a part of HR Excellence in Research strategy.

Requirements for the candidate:

1. Holds a Master's degree in biology, biochemistry or related field.

2. Eligibility for PhD studies in Poland.

3. Interests in molecular aspects of physiology, motivation for experimental work, passion for science, hands-on experience in laboratory work

4. Experience in mouse/rat-based studies or willingness to work with animals

5. Written and spoken fluency in English.

6. Willingness to learn and take new challenges, ability to work independently, analytical thinking.

7. Good interpersonal skills and a collaborative attitude.

8. Research achievements (eg, publications or manuscripts in preparation) and experience abroad will be of advantage.

We offer:

2. Full-time PhD scholarship for 48 months in amount: a) before the mid-term evaluation 3700 pln net/month; b) after mid-term evaluation 4500 pln net/month

3. Position with 100% focus on research (no teaching obligations)

4. Benefits including reduced-rate for an individual medical care package and membership in MultiSport programme

5. Full technical, administrative and organizational support from professional English-speaking personnel

6. Participation in courses, scientific training, support from peers, and academic mentoring

Deadline for applications is June 6^th, 2021. The summer semester at the Doctoral School shall begin on October 1^st, 2021.

How to apply:

• Apply via website https://bit.ly/3wMdVhX (the application system will be activated from 24^th May, 2021 deadline for sending application is 6^th June, 2021).  If you have any enquiries about the recruitment process or the project, please send your request to Ten adres pocztowy jest chroniony przed spamowaniem. Aby go zobaczyć, konieczne jest włączenie w przeglądarce obsługi JavaScript.

• Please include the following statement in your email: “I hereby agree to the processing of my personal data, included in the application documents by the International Institute of Molecular and Cell Biology in Warsaw, 4 Księcia Trojdena Street,02-109 Warsaw, for the purpose of carrying out the current recruitment process.” Your personal data will be processed for the purpose of the recruitment procedure by the International Institute of Molecular and Cell Biology in Warsaw. Full information is available under the link https://bit.ly/3mHTvSl