Publikacje

Porebska N, Pozniaka M, Krzyscik MA, Knapika A, Czyrek A, Kucinska M, Jastrzebski K, Zakrzewska M, Otlewski J, Opalinski L.

Dissecting biological activities of fibroblast growth factor receptors by the coiled-coil-mediated oligomerization of FGF1.

Int J Biol Macromol.

Kolmus K, Erdenebat P, Szymańska E, Stewig B, Goryca K, Derezinska-Wolek E, Szumera-Cieckiewicz A, Brewinska-Olchowik M, Piwocka K, Prochorec-Sobieszek M, Mikula M, Miaczynska M.

Concurrent depletion of Vps37 proteins evokes ESCRT-I destabilization and profound cellular stress responses.

J Cell Sci.

Maksymowicz M, Miączyńska M, Banach-Orłowska M.

Clathrin- and dynamin-dependent endocytosis limits canonical NF-κB signaling triggered by lymphotoxin β receptor.

Cell Commun Signal.

Cendrowski J, Miaczynska M.

Splicing variants of an endocytic regulator, BMP2K, differentially control autophagic degradation in erythroid cells.

Autophagy

Cendrowski J, Kaczmarek M, Mazur M, Kuzmicz-Kowalska K, Jastrzebski K, Brewinska-Olchowik M, Kominek A, Piwocka K, Miaczynska M.

Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells.

eLife

Pozniak M, Sokolowska-Wedzina A, Jastrzebski K, Szymczyk J, Porebska N, Krzyscik MA, Zakrzewska M, Miaczynska M, Otlewski J, Opalinski L.

FGFR1 Clustering With Engineered Tetravalent Antibody Improves the Efficiency and Modifies the Mechanism of Receptor Internalization.

Mol Oncol.

 Miaczynska M, Munson M.

Membrane Trafficking: Vesicle Formation, Cargo Sorting and Fusion.

Mol Biol Cell.

Szymańska E, Nowak P, Kolmus K, Cybulska M, Goryca K, Derezińska-Wołek E, Szumera-Ciećkiewicz A, Brewińska-Olchowik M, Grochowska A, Piwocka K, Prochorec-Sobieszek M, Mikula M, Miączyńska M.

Synthetic lethality between VPS4A and VPS4B triggers an inflammatory response in colorectal cancer.

EMBO Mol Med.

Banach-Orłowska M, Wyszyńska R, Pyrzyńska B, Maksymowicz M, Gołąb J, Miączyńska M.

Cholesterol restricts lymphotoxin β receptor-triggered NF-κB signaling.

Cell Commun Signal.

Budick-Harmelin N, Miaczynska M.

Integration of the Endocytic System into the Network of Cellular Functions.

Prog Mol Subcell Biol.

Banach-Orłowska M, Jastrzębski K, Cendrowski J, Maksymowicz M, Wojciechowska K, Korostyński M, Moreau D, Gruenberg J, Miaczynska M.

The topology of lymphotoxin β receptor accumulated upon endolysosomal dysfunction dictates the NF-κB signaling outcome.

J Cell Sci.

Szymanska E, Budick-Harmelin N, Miaczynska M.

Endosomal "sort" of signaling control: The role of ESCRT machinery in regulation of receptor-mediated signaling pathways.

Semin Cell Dev Biol.

Jastrzębski K, Zdżalik-Bielecka D, Mamińska A, Kalaidzidis Y, Hellberg C, Miaczynska M

Multiple routes of endocytic internalization of PDGFRβ contribute to PDGF-induced STAT3 signaling

J Cell Sci.

Tudek B, Zdżalik-Bielecka D, Tudek A, Kosicki K, Fabisiewicz A, Speina E

Lipid peroxidation in face of DNA damage, DNA repair and other cellular processes

Free Radic Biol Med

Mikula M, Skrzypczak M, Goryca K, Paczkowska K, Ledwon JK, Statkiewicz M, Kulecka M, Grzelak M, Dabrowska M, Kuklinska U, Karczmarski J, Rumienczyk I, Jastrzebski K, Miaczynska M, Ginalski K, Bomsztyk K, Ostrowski J.

Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy.

Nucleic Acids Res

Cendrowski J, Mamińska A, Miaczynska M

Endocytic regulation of cytokine receptor signaling

Cytokine Growth Factor Rev

Song J, Mu Y, Li C, Bergh A, Miaczynska M, Heldin CH, Landström M

APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain

Oncotarget

Mamińska A, Bartosik A, Banach-Orłowska M, Pilecka I, Jastrzębski K, Zdżalik-Bielecka D, Castanon I, Poulain M, Neyen C, Wolińska-Nizioł L, Toruń A, Szymańska E, Kowalczyk A, Piwocka K, Simonsen A, Stenmark H, Fürthauer M, González-Gaitán M, Miaczynska M

ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors

Sci Signal

Szymanska E, Skowronek A, Miaczynska M

Impaired dynamin 2 function leads to increased AP-1 transcriptional activity through the JNK/c-Jun pathway

Cell Signal

Kalaidzidis I, Miaczynska M, Brewińska-Olchowik M, Hupalowska A, Ferguson C, Parton RG, Kalaidzidis Y, Zerial M

APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments

J Cell Biol

Banach-Orlowska M, Szymanska E, Miaczynska M

APPL1 endocytic adaptor as a fine tuner of Dvl2-induced transcription

FEBS Lett

Torun A, Szymańska E, Castanon I, Wolińska-Nizioł L, Bartosik A, Jastrzębski K, Miętkowska M, González-Gaitán M, Miaczynska M

Endocytic adaptor protein Tollip inhibits canonical Wnt signaling

PLoS One

Kolanczyk M, Krawitz P, Hecht J, Hupalowska A, Miaczynska M, Marschner K, Schlack C, Emerich D, Kobus K, Kornak U, Robinson PN, Plecko B, Grangl G, Uhrig S, Mundlos S, Horn D

Missense variant in CCDC22 causes X-linked recessive intellectual disability with features of Ritscher-Schinzel/3C syndrome

Eur J Hum Genet

Sadowski Ł, Jastrzębski K, Purta E, Hellberg C, Miaczynska M

Labeling of platelet-derived growth factor by reversible biotinylation to visualize its endocytosis by microscopy

Methods Enzymol.

Miaczynska M

Effects of membrane trafficking on signaling by receptor tyrosine kinases

Cold Spring Harb Perspect Biol.

Sadowski L, Jastrzębski K, Kalaidzidis Y, Heldin CH, Hellberg C, Miaczynska M

Dynamin Inhibitors Impair Endocytosis and Mitogenic Signaling of PDGF

Traffic

Pyrzynska B, Banach-Orlowska M, Teperek-Tkacz M, Miekus K, Drabik G, Majka M, Miaczynska M

Multifunctional protein APPL2 contributes to survival of human glioma cells

Mol Oncol.

Winiarska M, Nowis D, Bil J, Glodkowska-Mrowka E, Muchowicz A, Wanczyk M, Bojarczuk K, Dwojak M, Firczuk M, Wilczek E, Wachowska M, Roszczenko K, Miaczynska M, Chlebowska J, Basak GW, Golab J

Prenyltransferases Regulate CD20 Protein Levels and Influence Anti-CD20 Monoclonal Antibody-mediated Activation of Complement-dependent Cytotoxicity

J Biol Chem

Zerrouqi A, Pyrzynska B, Febbraio M, Brat DJ, Van Meir EG

P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3

J Clin Invest.

Hupalowska A, Pyrzynska B, Miaczynska M

APPL1 regulates basal NF-κB activity by stabilizing NIK

J Cell Sci

Hupalowska A, Miaczynska M

The new faces of endocytosis in signaling

Traffic

Urbanska A, Sadowski L, Kalaidzidis Y, Miaczynska M

Biochemical characterization of APPL endosomes: the role of annexin A2 in APPL membrane recruitment

Traffic

Pilecka I, Sadowski L, Kalaidzidis Y, Miaczynska M

Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment

Exp Cell Res

Miaczynska M, Bar-Sagi D

Signaling endosomes: seeing is believing

Curr Opin Cell Biol

Ohya T, Miaczynska M, Coskun U, Lommer B, Runge A, Drechsel D, Kalaidzidis Y, Zerial M

Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.

Nature

Olchowik M, Miaczyńska M

[Effectors of GTPase Rab5 in endocytosis and signal transduction]

Postepy Biochem

Banach-Orlowska M, Pilecka I, Torun A, Pyrzynska B, Miaczynska M

Functional characterization of the interactions between endosomal adaptor protein APPL1 and the NuRD co-repressor complex

Biochem J

Sadowski L, Pilecka I, Miaczynska M

Signaling from endosomes: location makes a difference.

Exp Cell Res

Rashid S, Pilecka I, Torun A, Olchowik M, Bielinska B, Miaczynska M

Endosomal adaptor proteins APPL1 and APPL2 are novel activators of beta-catenin/TCF-mediated transcription.

J Biol Chem

Pyrzynska B, Pilecka I, Miaczynska M

Endocytic proteins in the regulation of nuclear signaling, transcription and tumorigenesis

Mol Oncol

Kubiak JZ, Ciemerych MA, Hupalowska A, Sikora-Polaczek M, Polanski Z

On the transition from the meiotic to mitotic cell cycle during early mouse development.

Int J Dev Biol

Miaczynska M, Stenmark H

Mechanisms and functions of endocytosis.

J Cell Biol

Pilecka I, Banach-Orlowska M, Miaczynska M

Nuclear functions of endocytic proteins

Eur J Cell Biol